The results of a Phase IIb randomized, controlled, double-blind trial conducted at the Clinical Research Unit of Nanoro (CRUN) / Institut de Recherche en Sciences de la Santé (IRSS), Burkina Faso indicate 77% efficacy over 12 months of follow-up for a vaccine that targets malaria caused by Plasmodium falciparum. The…


A small randomized, double-blind clinical trial published in RMD Open showed colchicine to be safe and effective in treating moderate to severe COVID-19 infections in hospitalized patients. In the study, patients who took the inexpensive drug required supplemental oxygen and hospitalization for less time. …


Most bats do not have rabies. According to the US Centers for Disease Control and Prevention (CDC), even among bats submitted for rabies testing, only about 6% had rabies. Rabies can only be confirmed in a laboratory but any bat that is active by day or is found in a…


Over 2 years since the Kivu Ebola epidemic began in August 2018, the US Food and Drug Administration (FDA) approved the first antibody cocktail for the treatment for Zaire ebolavirus (Ebola virus) infection in adult and pediatric patients. The drug, called Inmazeb, was developed by Regeneron — a biotech company…


UPDATE [January 2021]: The pathophysiology of chilblains (“COVID toes”) is still widely debated. An association with SARS-CoV-2 infection remains unconfirmed. Conflicting current evidence highlights the need for systematic and repeated testing of larger numbers of patients and the need for valid follow-up data.


COVID-19 spreads this way. Thanks for this excellent visual, Marcel Salathe & Nicky Case!

A study published mid-April reported that people infected with SARS-CoV-2, the coronavirus causing COVID-19, might be most contagious during the period before they have symptoms. Two studies published in late May showed that a high percentage of people with COVID-19 could be without symptoms. In one study, Australian researchers reported…


Previous studies have demonstrated that SARS-CoV-2, the virus that causes COVID-19, is stable on surfaces for extended periods under indoor conditions. A research in China demonstrated sustained coronavirus transmission despite changing weather conditions in different parts of the country that ranged from cold and dry to warm and humid. A…


A phase 2 trial has shown that a 2-week course of triple antiviral therapy with (1) interferon beta-1b (used to treat the relapsing-remitting and progressive forms of multiple sclerosis), (2) lopinavir-ritonavir (for the treatment of HIV/AIDS) and (3) ribavirin (used to treat chronic hepatitis C and other flavivirus infections) is…


April 25 marks “World Malaria Day,” which is celebrated every year to recognize global efforts to control the disease, to commemorate those who have been affected by it, and to highlight the need for continued investment in and sustained political commitment to malaria prevention and control.

Dr. Melvin Sanicas

Physician-Scientist FRSPH FRSA • GlobalHealth | Infectious Diseases | Digital Health • Writes about innovation, vaccines, pathogens, outbreaks, public health

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